EndoC-βH5® brings you absolute flexibility: A unique thaw and go human beta cell solution

Option 1: Please anticipate delay for applying to an USDA import permit (~2-3 months)
Option 2: Please select our BSA-free versions of Ulti β 1®, Ulti-ST® and Opti β Max®: Ultiβ1-BF® , Ulti-ST-BF® and OptiβMax-BF® (note these versions requires addition of BSA before use)

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10/03/2022 By Human Cell Design Comments are Off BH5, T1D, T2D

Don’t always wait for human pancreatic islet samples. EndoC-βH5 is a flexible solution of human beta cells that can be used at any time.

See here an illustration of the use of EndoC-βH5® cells from thawing to functional assay (e.g. glucose stimulated insulin secretion, GSIS).

EndoC-βH5® cells are fully mature human pancreatic beta cells that exhibit characteritics of native beta cell (i.e. dose dependent glucose stimulated insulin secretion, dose dependent insulin secretion upon GLP1R and GIPR agonists, elevated total insulin content, expression of mature beta cell markers).

More than an alternative solution, Human Cell Design team has worked for years to address the limitations and simplify the work of the Diabetes research community that uses primary islets with:

Thaw and go solution
Batch to Batch reproducibility
Unlimited quantity
Modeling

EndoC-βH5® are available as reproducible and validated frozen batches and represent a unique and powerful tool for drug discovery, preclinical modeling and fundamental research using human pancreatic beta cells.