BRIDGING THE GAP BETWEEN PRECLINICAL AND CLINICAL DATA USING HUMAN ASSAYS

REVEAL THE REAL POTENTIAL OF YOUR DRUG DISCOVERY PROGRAM USING HUMAN STANDARDIZED DISEASE MODELS

Human Cell Design is a Contract Research Organization which combines a unique 2D/3D human disease models panel with high expertise in human cell biology and physiology. We provide customized solutions for accelerating clinically relevant scientific progress. From target validation to preclinical validation our experts provide you with long term strategies and help you develop stables readouts and valuable deliverables. We share the same goal by generating robust data to independently leverage your project real potential.

GET MORE INFORMATION ON HUMAN CELL DESIGN SERVICE EXPERTISE

CUSTOM PRE-CLINICAL SERVICES DEDICATED TO DRUGS TARGETING TYPE I AND 2 DIABETES

TYPE 1 & 2 DIABETES:

  • Target Validation
  • Glucolipotoxicity
  • Inflammation mediated diabetes
  • Immuno-dependant beta cell destruction
  • Insulin Secretion
  • 3D sphere model
Contact us

GET MORE INFORMATION ON HUMAN CELL DESIGN SERVICE EXPERTISE

CUSTOM PRE-CLINICAL SERVICES DEDICATED TO DRUGS TARGETING TYPE I AND 2 DIABETES

TYPE 1 & 2 DIABETES:
Target Validation
Glucolipotoxicity
Inflammation mediated diabetes
Immuno-dependant beta cell destruction
Insulin Secretion
3D sphere model

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Dr. Thomas Frogne
NOVO NORDISK

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.

MOLECULAR METABOLISM

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Dr. Norbert Tennagels
SANOFI

Acute and repeated treatment with 5-PAHSA or 9-PAHSA isomers does not improve glucose control in mice.

CELL METABOLISM

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Dr. Pia Davidsson
ASTRAZENECA

Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.

PLOS ONE

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Dr. Axel Haup
ELI LILLY

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.

MOLECULAR METABOLISM

TRULY TRANSLATIONAL HUMAN CELL MODELS

GETTING BETTER MEDICATION TO PATIENTS FASTER

Here at Human Cell Design, we are convinced that human cell models are the way forward to getting better medication to patients faster. Our customers in the pharmaceutical and biotech industries and in academia rely on our internationally recognized human cells to generate reproducible data and to make informed decisions early in the drug development process.

Learn more

TRULY TRANSLATIONAL HUMAN CELL MODELS

GETTING BETTER MEDICATION TO PATIENTS FASTER

Here at Human Cell Design, we are convinced that human cell models are the way forward to get better medication to patients faster. Our customers in the pharmaceutical and biotech industries and in academia rely on our internationally recognized human cells to generate reproducible data and make informed decisions early in the drug development process.

VALIDATED BY OVER

INTERNATIONAL INSTITUTIONS

Accelerate and secure your Drug Discovery program using unique standardized disease models and assays

ROBUST
SCALABLE
DISEASE RELEVANT
PHYSIOLOGICAL
SENSITIVE
DATA REPRODUCIBILITY

A PATENTED CELL MATURATION PLATFORM

FOR LARGE-SCALE PRODUCTION OF FUNCTIONAL HUMAN CELLS

To overcome industrial bottlenecks and provide truly translational human cell models for R&D, Human Cell Design combines the potential of human iPSC technology or human primary cells with a patented maturation platform. Our NatLine Platform® amplifies and maturates hiPSC-derived and primary progenitor cells to provide unlimited quantities of truly mature and functional human cells. The produced terminally differentiated cells replicate native adult human cells. NatLine® platform is adapted to large-scale and reproducible production of healthy or diseased human cell models.

Learn more

A PATENTED CELL MATURATION PLATFORM

FOR LARGE-SCALE PRODUCTION OF FUNCTIONAL HUMAN CELLS

To overcome industrial bottlenecks and provide truly translational human cell models for R&D, Human Cell Design combines the potential of human iPSC technology or human primary cells with a patented maturation platform. Our NatLine Platform® amplifies and maturates hiPSC-derived and primary progenitor cells to provide unlimited quantities of truly mature and functional human cells. The produced terminally differentiated cells replicate native adult human cells. NatLine® platform is adapted to large-scale and reproducible production of healthy or diseased human cell models.

LATEST NEWS

HLA-A2 βH5® cell line for Type 1 Diabetes research

Revolutionize your Autoimmune-mediated T1D Research: HLA-A2 βH5® Cell Line Open new avenue using a unique clinically relevant cell model. HLA-A2 EndoC-βH5® is a new human pancreatic beta cell line that has ...

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OptiβMax®, a new medium for EndoC-βH1® cells

Fed up with low Endoc-βH1® amplification rate and months of culturing to get the cell number you need? Want to get results faster, not wasting time with improved robustness using Endoc-βH1® human beta ...

Read more

Webinar: Type 1 and Type 2 Diabetes in a dish

Bruno Blanchi, PhD, and Miguel Sáinz Jaspeado, PhD, presented last highlights on new physiological Type 1 and 2 diabetes assays using human cell design Endoc-BH cells and Mercodia Elisa expertise Thursday, ...

Read more

LATEST NEWS

HLA-A2 βH5® cell line for Type 1 Diabetes research

Revolutionize your Autoimmune-mediated T1D Research: HLA-A2 βH5® Cell Line Open new avenue using a unique clinically relevant cell model. HLA-A2 EndoC-βH5® is a new human pancreatic beta cell line that has ...

Read more

OptiβMax®, a new medium for EndoC-βH1® cells

Fed up with low Endoc-βH1® amplification rate and months of culturing to get the cell number you need? Want to get results faster, not wasting time with improved robustness using Endoc-βH1® human beta ...

Read more

Webinar: Type 1 and Type 2 Diabetes in a dish

Bruno Blanchi, PhD, and Miguel Sáinz Jaspeado, PhD, presented last highlights on new physiological Type 1 and 2 diabetes assays using human cell design Endoc-BH cells and Mercodia Elisa expertise Thursday, ...

Read more

Human Cell Design scientists are proud to present at the 59th EASD two new and innovative human T1D & T2D cell models

Human Cell Design scientists are proud to present at the 59th EASD two new and innovative human T1D & T2D cell models Hamburg, October 2-6, 2023  This year many EASD talks demonstrated the relevance of ...

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