BRIDGING THE GAP BETWEEN PRECLINICAL AND CLINICAL DATA USING HUMAN ASSAYS
REVEAL THE REAL POTENTIAL OF YOUR DRUG DISCOVERY PROGRAM USING HUMAN STANDARDIZED DISEASE MODELS
Human Cell Design is a Contract Research Organization which combines a unique 2D/3D human disease models panel with high expertise in human cell biology and physiology. We provide customized solutions for accelerating clinically relevant scientific progress. From target validation to preclinical validation our experts provide you with long term strategies and help you develop stables readouts and valuable deliverables. We share the same goal by generating robust data to independently leverage your project real potential.
GET MORE INFORMATION ON HUMAN CELL DESIGN SERVICE EXPERTISE
CUSTOM PRE-CLINICAL SERVICES DEDICATED TO DRUGS TARGETING TYPE I AND 2 DIABETES
TYPE 1 & 2 DIABETES:
- Target Validation
- Glucolipotoxicity
- Inflammation mediated diabetes
- Immuno-dependant beta cell destruction
- Insulin Secretion
- 3D sphere model
GET MORE INFORMATION ON HUMAN CELL DESIGN SERVICE EXPERTISE
CUSTOM PRE-CLINICAL SERVICES DEDICATED TO DRUGS TARGETING TYPE I AND 2 DIABETES
TYPE 1 & 2 DIABETES:
Target Validation
Glucolipotoxicity
Inflammation mediated diabetes
Immuno-dependant beta cell destruction
Insulin Secretion
3D sphere model
Dr. Thomas Frogne
NOVO NORDISK
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.
MOLECULAR METABOLISM
Dr. Norbert Tennagels
SANOFI
Acute and repeated treatment with 5-PAHSA or 9-PAHSA isomers does not improve glucose control in mice.
CELL METABOLISM
Dr. Pia Davidsson
ASTRAZENECA
Secretagogin is increased in plasma from type 2 diabetes patients and potentially reflects stress and islet dysfunction.
PLOS ONE
Dr. Axel Haup
ELI LILLY
LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.
MOLECULAR METABOLISM
TRULY TRANSLATIONAL HUMAN CELL MODELS
GETTING BETTER MEDICATION TO PATIENTS FASTER
Here at Human Cell Design, we are convinced that human cell models are the way forward to getting better medication to patients faster. Our customers in the pharmaceutical and biotech industries and in academia rely on our internationally recognized human cells to generate reproducible data and to make informed decisions early in the drug development process.
TRULY TRANSLATIONAL HUMAN CELL MODELS
GETTING BETTER MEDICATION TO PATIENTS FASTER
Here at Human Cell Design, we are convinced that human cell models are the way forward to get better medication to patients faster. Our customers in the pharmaceutical and biotech industries and in academia rely on our internationally recognized human cells to generate reproducible data and make informed decisions early in the drug development process.
VALIDATED BY OVER
INTERNATIONAL INSTITUTIONS
Accelerate and secure your Drug Discovery program using unique standardized disease models and assays
ROBUST
SCALABLE
DISEASE RELEVANT
PHYSIOLOGICAL
SENSITIVE
DATA REPRODUCIBILITY
A PATENTED CELL MATURATION PLATFORM
FOR LARGE-SCALE PRODUCTION OF FUNCTIONAL HUMAN CELLS
To overcome industrial bottlenecks and provide truly translational human cell models for R&D, Human Cell Design combines the potential of human iPSC technology or human primary cells with a patented maturation platform. Our NatLine Platform® amplifies and maturates hiPSC-derived and primary progenitor cells to provide unlimited quantities of truly mature and functional human cells. The produced terminally differentiated cells replicate native adult human cells. NatLine® platform is adapted to large-scale and reproducible production of healthy or diseased human cell models.
A PATENTED CELL MATURATION PLATFORM
FOR LARGE-SCALE PRODUCTION OF FUNCTIONAL HUMAN CELLS
To overcome industrial bottlenecks and provide truly translational human cell models for R&D, Human Cell Design combines the potential of human iPSC technology or human primary cells with a patented maturation platform. Our NatLine Platform® amplifies and maturates hiPSC-derived and primary progenitor cells to provide unlimited quantities of truly mature and functional human cells. The produced terminally differentiated cells replicate native adult human cells. NatLine® platform is adapted to large-scale and reproducible production of healthy or diseased human cell models.
LATEST NEWS
T1D and T2D Inflammation Assay
Reveal your drug’s anti-inflammatory and beta cell protection potential Using Endoc-BH5® cells, the Cytokine-Mediated Human Beta Cell Inflammation Assay replicates in vitro the clinically observed response ...
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5th European Incretin Study Group meeting
5th European Incretin Study Group meeting: Human Cell Design presents its last insulin and cAMP assay innovations Scientists from Human Cell Design participated in the 5th European Incretin Study Group meeting ...
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GLTx EndoC-βH5®
Revolutionize Your Glucolipotoxicity-Mediated T2D Research Open new avenue using a unique clinically relevant cell model. GLTx EndoC-βH5® is a new human pancreatic beta cell line that has been specifically ...
Read moreLATEST NEWS
T1D and T2D Inflammation Assay
Reveal your drug’s anti-inflammatory and beta cell protection potential Using Endoc-BH5® cells, the Cytokine-Mediated Human Beta Cell Inflammation Assay replicates in vitro the clinically observed response ...
Read more5th European Incretin Study Group meeting
5th European Incretin Study Group meeting: Human Cell Design presents its last insulin and cAMP assay innovations Scientists from Human Cell Design participated in the 5th European Incretin Study Group meeting ...
Read moreGLTx EndoC-βH5®
Revolutionize Your Glucolipotoxicity-Mediated T2D Research Open new avenue using a unique clinically relevant cell model. GLTx EndoC-βH5® is a new human pancreatic beta cell line that has been specifically ...
Read more
U.S Customers: New regulations on animal origin product imports
U.S Customers: New regulations on animal origin product imports U.S Customers: Due to recent more rigorous regulatory scrutiny on products containing animal-derived components, the U.S Customs now ...
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Due to recent more rigorous regulatory scrutiny on products containing animal-derived components, the U.S Customs now require a USDA import permit. This affects